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Sternal resection for tumor is a surgical procedure aimed at removing neoplastic growths located in or around the sternum, primarily due to malignancies such as chest wall tumors, sarcomas, or metastases from distant organ cancers. The sternum, also known as the breastbone, serves as a protective shield for vital organs such as the heart and lungs, and its structural integrity is crucial for normal respiratory function. This procedure typically arises in cases where tumors are directly invading the sternum or when surgical intervention is necessary to achieve clear margins, allowing for effective oncological treatment. Preoperative assessment is crucial and often involves imaging techniques such as CT scans and MRIs to delineate the tumor's extent, its relation to surrounding structures, and to identify any potential metastases. The surgical approach may vary based on the tumor's size, location, and type, but it commonly involves an incision in the midline of the chest, allowing for access to the sternum and adjacent tissues. The surgeon carefully dissects the soft tissue layers to reach the sternum, ensuring minimal trauma to surrounding anatomical structures. In some cases, a partial resection may be sufficient, where only the affected section of the sternum is excised, whereas more aggressive tumors may necessitate a complete sternal resection. During the procedure, meticulous attention is given to the vascular and neurological structures adjacent to the sternum, as their protection is critical to preventing postoperative complications. After the excision, the surgeon may reconstruct the chest wall to restore its stability and integrity, using synthetic materials or parts of adjacent tissues. Postoperatively, patients are closely monitored for complications such as infections, bleeding, or respiratory difficulties. Pain management becomes a significant part of the recovery process, as the resection can lead to significant discomfort due to the disruption of the chest wall. The involvement of a multidisciplinary team-including surgical oncologists, anesthesiologists, and rehabilitation specialists-ensures comprehensive care throughout the patient's journey. Rehabilitation is an essential aspect of recovery, focusing on gradually restoring the patient's respiratory function, strength, and overall quality of life. It is vital for patients to adhere to follow-up appointments, which include surveillance imaging and clinical evaluations to monitor for any signs of recurrence. The prognosis after sternal resection varies widely depending on the tumor type, stage at diagnosis, and patient health status. While some patients may achieve long-term survival following complete resection and adjuvant therapies, others may struggle with tumor recurrence, underscoring the need for ongoing management and support. In conclusion, sternal resection for tumor treatment is a complex procedure that demands precision and a comprehensive approach to enhance patient outcomes and ensure their return to normal activities following recovery.